A synthetic uric acid analog accelerates cutaneous wound healing in mice.

Wound healing is a complex process involving intrinsic dermal and epidermal cells, and infiltrating macrophages and leukocytes. Excessive oxidative stress and associated inflammatory processes can impair wound healing, and antioxidants have been reported to improve wound healing in animal models and...

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Bibliographic Details
Main Authors: Srinivasulu Chigurupati, Mohamed R Mughal, Sic L Chan, Thiruma V Arumugam, Akanksha Baharani, Sung-Chun Tang, Qian-Sheng Yu, Harold W Holloway, Ross Wheeler, Suresh Poosala, Nigel H Greig, Mark P Mattson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2850366?pdf=render