Characteristics and prognostic significance of genetic mutations in acute myeloid leukemia based on a targeted next‐generation sequencing technique

Characteristics and prognostic significance of genetic mutations in acute myeloid leukemia based on a targeted next‐generation sequencing technique

Abstract To explore the characteristics and prognostic significance of genetic mutations in acute myeloid leukemia (AML), we screened the gene mutation profile of 171 previously untreated AML patients using a next‐generation sequencing technique targeting 127 genes with potential prognostic signific...

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Bibliographic Details
Main Authors: Rui‐Qi Wang, Chong‐Jian Chen, Yu Jing, Jia‐Yue Qin, Yan Li, Guo‐Feng Chen, Wei Zhou, Yong‐Hui Li, Juan Wang, Da‐Wei Li, Hong‐Mei Zhao, Bian‐Hong Wang, Li‐Li Wang, Hong Wang, Meng‐Zhen Wang, Xiao‐Ning Gao, Li Yu
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Cancer Medicine
Subjects:
acute myeloid leukemia
genetic mutations
next‐generation sequencing
prognosis stratification
Online Access:https://doi.org/10.1002/cam4.3467

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