The Association Between Oxidative Stress Alleviation via Sulforaphane-Induced Nrf2-HO-1/NQO-1 Signaling Pathway Activation and Chronic Renal Allograft Dysfunction Improvement

The Association Between Oxidative Stress Alleviation via Sulforaphane-Induced Nrf2-HO-1/NQO-1 Signaling Pathway Activation and Chronic Renal Allograft Dysfunction Improvement

Background/Aims: Chronic renal allograft dysfunction (CRAD) is a leading cause of long-term renal allograft loss. Oxidative stress may account for the nonspecific interstitial fibrosis and tubular atrophy that occur in CRAD. An antioxidant intervention via Nrf2 signaling pathway activation might be...

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Bibliographic Details
Main Authors: Daoyuan Lv, Qin Zhou, Yue Xia, Xu You, Zhihong Zhao, Yongqiang Li, Hequn Zou
Format: Article
Language:English
Published: Karger Publishers 2018-02-01
Series:Kidney & Blood Pressure Research
Subjects:
Chronic renal allograft dysfunction
Oxidative stress
Nrf2
Sulforaphane
Online Access:https://www.karger.com/Article/FullText/487501

Internet

https://www.karger.com/Article/FullText/487501

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