Comparative Transcriptomics of Ex Vivo, Patient-Derived Endothelial Cells Reveals Novel Pathways Associated With Type 2 Diabetes Mellitus

Comparative Transcriptomics of Ex Vivo, Patient-Derived Endothelial Cells Reveals Novel Pathways Associated With Type 2 Diabetes Mellitus

Summary: In this study low-input RNA-sequencing was used to annotate the molecular identity of endothelial cells isolated and immunopurified with CD144 microbeads. Using this technique, comparative gene expression profiling from healthy subjects and patients with type 2 diabetes mellitus identified...

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Bibliographic Details
Main Authors: Joshua A. Beckman, MD, Sean P. Doherty, BA, Zachary B. Feldman, BA, Emily S. Banks, BS, Javid Moslehi, MD, Iris Z. Jaffe, MD, PhD, Naomi M. Hamburg, MD, Quanhu Sheng, PhD, Jonathan D. Brown, MD
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X19301810

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http://www.sciencedirect.com/science/article/pii/S2452302X19301810

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