Mechanistic studies of gene delivery into mammalian cells by electrical short-circuiting via an aqueous droplet in dielectric oil.

Mechanistic studies of gene delivery into mammalian cells by electrical short-circuiting via an aqueous droplet in dielectric oil.

We have developed a novel methodology for the delivery of cell-impermeable molecules, based on electrical short-circuiting via a water droplet in dielectric oil. When a cell suspension droplet is placed between a pair of electrodes with an intense DC electric field, droplet bouncing and droplet defo...

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Bibliographic Details
Main Authors: Hirofumi Kurita, Hirohito Nihonyanagi, Yuki Watanabe, Kenta Sugano, Ryuto Shinozaki, Kenta Kishikawa, Rika Numano, Kazunori Takashima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243361

Internet

https://doi.org/10.1371/journal.pone.0243361

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