Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells

Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells

<p>Abstract</p> <p>Background</p> <p>Translational control mediated by non-coding microRNAs (miRNAs) plays a key role in the mechanism of cellular resistance to anti-cancer drug treatment. Dihydrofolate reductase (DHFR) and thymidylate synthase (TYMS, TS) are two of the...

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Bibliographic Details
Main Authors: Formentini Andrea, Botchkina Galina, Titmus Matthew A, Wang Yuan, Song Bo, Kornmann Marko, Ju Jingfang
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/96

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