Decoding and reprogramming fungal iterative nonribosomal peptide synthetases

Nonribosomal peptides are important bioactive molecules that are synthetized by enzymes containing several catalytic domains. Here the authors describe the catalytic mechanism of fungal nonribosomal peptide synthetases and present an approach to modify these enzymes to produce specific nonribosomal...

Full description

Bibliographic Details
Main Authors: Dayu Yu, Fuchao Xu, Shuwei Zhang, Jixun Zhan
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15349