Long-range diastereoselectivity in Ugi reactions of 2-substituted dihydrobenzoxazepines

Long-range diastereoselectivity in Ugi reactions of 2-substituted dihydrobenzoxazepines

The Ugi reaction of 2-substituted dihydrobenzoxazepines was found to proceed with unexpectedly good diastereoselectivitiy (diastereoisomeric ratios up to 9:1), despite the large distance between the pre-existing stereogenic centre and the newly generated one. This result represents the first good 1,...

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Bibliographic Details
Main Authors:	Luca Banfi, Andrea Basso, Valentina Cerulli, Valeria Rocca, Renata Riva
Format:	Article
Language:	English
Published:	Beilstein-Institut 2011-07-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	benzoxazepines cyclic imines long range stereoinduction multicomponent reactions Ugi reaction
Online Access:	https://doi.org/10.3762/bjoc.7.109

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