Scavenger Receptors and Atherosclerosis
Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classe...
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2000-01-01
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doaj-b6f6584fb8d942528b18d71de0db49712020-11-24T23:55:28ZengBMCBiological Research0716-97600717-62872000-01-0133297103Scavenger Receptors and AtherosclerosisATTILIO RIGOTTIScavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classes of scavenger receptors have been identified, and their relevance in normal and pathological conditions is under investigation. Recent in vitro and in vivo studies strongly support the role of class A and class B scavenger receptors in lipid transport atherogenesishttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009atherosclerosischolesterol metabolismlipoproteinscavenger receptorselective cholesterol uptake |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
ATTILIO RIGOTTI |
spellingShingle |
ATTILIO RIGOTTI Scavenger Receptors and Atherosclerosis Biological Research atherosclerosis cholesterol metabolism lipoprotein scavenger receptor selective cholesterol uptake |
author_facet |
ATTILIO RIGOTTI |
author_sort |
ATTILIO RIGOTTI |
title |
Scavenger Receptors and Atherosclerosis |
title_short |
Scavenger Receptors and Atherosclerosis |
title_full |
Scavenger Receptors and Atherosclerosis |
title_fullStr |
Scavenger Receptors and Atherosclerosis |
title_full_unstemmed |
Scavenger Receptors and Atherosclerosis |
title_sort |
scavenger receptors and atherosclerosis |
publisher |
BMC |
series |
Biological Research |
issn |
0716-9760 0717-6287 |
publishDate |
2000-01-01 |
description |
Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classes of scavenger receptors have been identified, and their relevance in normal and pathological conditions is under investigation. Recent in vitro and in vivo studies strongly support the role of class A and class B scavenger receptors in lipid transport atherogenesis |
topic |
atherosclerosis cholesterol metabolism lipoprotein scavenger receptor selective cholesterol uptake |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009 |
work_keys_str_mv |
AT attiliorigotti scavengerreceptorsandatherosclerosis |
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