Scavenger Receptors and Atherosclerosis

Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classe...

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Main Author: ATTILIO RIGOTTI
Format: Article
Language:English
Published: BMC 2000-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009
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spelling doaj-b6f6584fb8d942528b18d71de0db49712020-11-24T23:55:28ZengBMCBiological Research0716-97600717-62872000-01-0133297103Scavenger Receptors and AtherosclerosisATTILIO RIGOTTIScavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classes of scavenger receptors have been identified, and their relevance in normal and pathological conditions is under investigation. Recent in vitro and in vivo studies strongly support the role of class A and class B scavenger receptors in lipid transport atherogenesishttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009atherosclerosischolesterol metabolismlipoproteinscavenger receptorselective cholesterol uptake
collection DOAJ
language English
format Article
sources DOAJ
author ATTILIO RIGOTTI
spellingShingle ATTILIO RIGOTTI
Scavenger Receptors and Atherosclerosis
Biological Research
atherosclerosis
cholesterol metabolism
lipoprotein
scavenger receptor
selective cholesterol uptake
author_facet ATTILIO RIGOTTI
author_sort ATTILIO RIGOTTI
title Scavenger Receptors and Atherosclerosis
title_short Scavenger Receptors and Atherosclerosis
title_full Scavenger Receptors and Atherosclerosis
title_fullStr Scavenger Receptors and Atherosclerosis
title_full_unstemmed Scavenger Receptors and Atherosclerosis
title_sort scavenger receptors and atherosclerosis
publisher BMC
series Biological Research
issn 0716-9760
0717-6287
publishDate 2000-01-01
description Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classes of scavenger receptors have been identified, and their relevance in normal and pathological conditions is under investigation. Recent in vitro and in vivo studies strongly support the role of class A and class B scavenger receptors in lipid transport atherogenesis
topic atherosclerosis
cholesterol metabolism
lipoprotein
scavenger receptor
selective cholesterol uptake
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009
work_keys_str_mv AT attiliorigotti scavengerreceptorsandatherosclerosis
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