TMAO: a potential mediator of clopidogrel resistance

Abstract Trimethylamine-N-oxide (TMAO) can activate platelets and increase thrombosis risk in clinical and experimental models. Meanwhile, the patients with coronary artery disease have higher serum TMAO level. However, it remains unknown whether Clopidogrel Resistance (CR) could be attributed to TM...

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Bibliographic Details
Main Authors: Ruisong Ma, Wenwen Fu, Jing Zhang, Xiaorong Hu, Jun Yang, Hong Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85950-8