Employment of Alginate Floating In Situ Gel for Controlled Delivery of Celecoxib: Solubilization and Formulation Studies
Celecoxib (CXB) is a COX-2-selective nonsteroidal anti-inflammatory drug used to control pain and various inflammatory conditions. CXB has limited oral bioavailability and a slow dissociation rate due to its poor water solubility. In order to enhance the oral bioavailability of CXB and reduce the fr...
Main Authors: | Bazigha K. Abdul Rasool, AlZahraa Khalifa, Eman Abu-Gharbieh, Rawoof Khan |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2020/1879125 |
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