Phospho-proteomic analysis of primary human colon epithelial cells during the early Trypanosoma cruzi infection phase.

The protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease, causes severe morbidity and mortality in afflicted individuals. About 30% of T. cruzi-infected individuals present with cardiac, gastrointestinal tract, and/or neurological disorders. Megacolon, one of the major patholo...

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Bibliographic Details
Main Authors: Shankar Suman, Girish Rachakonda, Sammed N Mandape, Shruti S Sakhare, Fernando Villalta, Siddharth Pratap, Maria F Lima, Pius N Nde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0006792