A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)

A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)

In this paper, histamine sensing by surface plasmon resonance (SPR) spectroscopy using an electropolymerized molecularly imprinted polymer (E-MIP) of functionalized polyterthiophene and histamine is reported. The MIP histamine sensor showed good linear relationship (R2 = 0.995) between the SPR angle...

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Main Authors: Hubilla Frances Adeline D., Mabilangan Arvin I., Advincula Rigoberto C., del Mundo Florian R.
Format: Article
Language:English
Published: EDP Sciences 2017-01-01
Series:MATEC Web of Conferences
Online Access:https://doi.org/10.1051/matecconf/20179502006
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spelling doaj-b6e0d13554cf4421a8c36422158b3fd62021-02-02T00:14:38ZengEDP SciencesMATEC Web of Conferences2261-236X2017-01-01950200610.1051/matecconf/20179502006matecconf_icmme2017_02006A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)Hubilla Frances Adeline D.Mabilangan Arvin I.Advincula Rigoberto C.del Mundo Florian R.In this paper, histamine sensing by surface plasmon resonance (SPR) spectroscopy using an electropolymerized molecularly imprinted polymer (E-MIP) of functionalized polyterthiophene and histamine is reported. The MIP histamine sensor showed good linear relationship (R2 = 0.995) between the SPR angle shift and the logarithm of histamine concentration, ranging from 15 – 500 μg/mL, with a limit of detection (LOD) of 2.0 μg/mL and a calibration sensitivity of 44.6 m° per log μg/mL histamine. Results also showed higher binding affinity of histamine for the MIP sensor than for the non-imprinted (NIP) sensor indicating excellent specificity. Moreover, the selectivity of the MIP histamine sensor against some of its structural analogues was demonstrated.https://doi.org/10.1051/matecconf/20179502006
collection DOAJ
language English
format Article
sources DOAJ
author Hubilla Frances Adeline D.
Mabilangan Arvin I.
Advincula Rigoberto C.
del Mundo Florian R.
spellingShingle Hubilla Frances Adeline D.
Mabilangan Arvin I.
Advincula Rigoberto C.
del Mundo Florian R.
A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)
MATEC Web of Conferences
author_facet Hubilla Frances Adeline D.
Mabilangan Arvin I.
Advincula Rigoberto C.
del Mundo Florian R.
author_sort Hubilla Frances Adeline D.
title A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)
title_short A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)
title_full A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)
title_fullStr A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)
title_full_unstemmed A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)
title_sort surface plasmon resonance histamine sensor based on an electropolymerized molecularly imprinted polymer (e-mip)
publisher EDP Sciences
series MATEC Web of Conferences
issn 2261-236X
publishDate 2017-01-01
description In this paper, histamine sensing by surface plasmon resonance (SPR) spectroscopy using an electropolymerized molecularly imprinted polymer (E-MIP) of functionalized polyterthiophene and histamine is reported. The MIP histamine sensor showed good linear relationship (R2 = 0.995) between the SPR angle shift and the logarithm of histamine concentration, ranging from 15 – 500 μg/mL, with a limit of detection (LOD) of 2.0 μg/mL and a calibration sensitivity of 44.6 m° per log μg/mL histamine. Results also showed higher binding affinity of histamine for the MIP sensor than for the non-imprinted (NIP) sensor indicating excellent specificity. Moreover, the selectivity of the MIP histamine sensor against some of its structural analogues was demonstrated.
url https://doi.org/10.1051/matecconf/20179502006
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