Interleukin-10-dependent down-regulation of interferon-gamma response to Leishmania by Mycobacterium leprae antigens during the clinical course of a coinfection

Interleukin-10-dependent down-regulation of interferon-gamma response to Leishmania by Mycobacterium leprae antigens during the clinical course of a coinfection

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We have described a case of a patient with an intriguing association of mucocutaneous leishmaniasis with lepromatous leprosy, two opposite polar forms of these spectral diseases. In the present follow-up study, we investigated the effect of the addition of Mycobacterium leprae antigens on interferon...

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Bibliographic Details
Main Authors: R.B.G. Azeredo-Coutinho, D.C.S. Matos, J.A.C. Nery, C.M. Valete-Rosalino, S.C.F. Mendonça
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Interferon-gamma
Interleukin-10
Mucocutaneous leishmaniasis
Lepromatous leprosy
Leishmania braziliensis
Mycobacterium leprae
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000700010&lng=en&tlng=en

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