An electron transfer competent structural ensemble of membrane-bound cytochrome P450 1A1 and cytochrome P450 oxidoreductase
Mukherjee, Nandekar and Wade investigate the structural arrangement of the complex between membrane-bound cytochrome P450 1A1 and NADPH-cytochrome P450 reductase. They find that upon binding to the reductase, the catalytic domain of cytochrome P450 1A1 reorients subject to the constraints of membran...
Main Authors: | Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-020-01568-y |
Similar Items
-
Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450
by: Diana Campelo, et al.
Published: (2018-12-01) -
Structure and dynamics of the membrane-bound cytochrome P450 2C9.
by: Vlad Cojocaru, et al.
Published: (2011-08-01) -
Biochemical analysis of microsomal NADPH-cytochrome P450 oxidoreductase and carboxylesterase
by: Smith, Graeme Cameron Murray
Published: (1995) -
Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase
by: Simon Bo Jensen, et al.
Published: (2021-04-01) -
Cytochrome P450 oxidoreductase deficiency: Novel cause of ambiguity with primary amenorrhea
by: Kranti Shreesh Khadilkar, et al.
Published: (2017-01-01)