Backward Hopf bifurcation in a mathematical model for oncolytic virotherapy with the infection delay and innate immune effects

In this paper, we consider a system of delay differential equations that models the oncolytic virotherapy on solid tumours with the delay of viral infection in the presence of the innate immune response. We conduct qualitative and numerical analysis, and provide possible medical implications for our...

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Bibliographic Details
Main Authors: Yuxiao Guo, Ben Niu, Jianjun Paul Tian
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Biological Dynamics
Subjects:
Online Access:http://dx.doi.org/10.1080/17513758.2019.1667443