ELAC2, an Enzyme for tRNA Maturation, Plays a Role in the Cleavage of a Mature tRNA to Produce a tRNA-Derived RNA Fragment During Respiratory Syncytial Virus Infection

ELAC2, an Enzyme for tRNA Maturation, Plays a Role in the Cleavage of a Mature tRNA to Produce a tRNA-Derived RNA Fragment During Respiratory Syncytial Virus Infection

Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infection in young children. However, effective treatment against RSV is unavailable. tRNA-derived RNA fragments (tRFs) are a recently discovered family of non-coding RNAs. We made an early observation that RSV inf...

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Bibliographic Details
Main Authors: Eun-Jin Choi, Wenzhe Wu, Ke Zhang, Inhan Lee, In-Hoo Kim, Yong Sun Lee, Xiaoyong Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
RSV
tRF
biogenesis
ELAC2
viral replication
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.609732/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2020.609732/full

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