Modulation and bioinformatics screening of hepatic mRNA-lncRNAs (HML) network associated with insulin resistance in prediabetic and exercised mice

Modulation and bioinformatics screening of hepatic mRNA-lncRNAs (HML) network associated with insulin resistance in prediabetic and exercised mice

Abstract Background Insulin resistance is associated with prediabetes and further progression to type 2 diabetes mellitus (T2DM). This study aims to investigate novel hepatic lncRNAs associated with key genes in insulin resistance in prediabetes. Methods In the bioinformatics phase, we have collecte...

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Bibliographic Details
Main Authors: Fatemeh Kazeminasab, Sayed Mohammad Marandi, Maryam Baharlooie, Mohammad Hossein Nasr-Esfahani, Kamran Ghaedi
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Nutrition & Metabolism
Subjects:
Endurance exercise
Insulin resistance
lncRNA
Non-alcoholic fatty liver disease
Prediabetes
Online Access:https://doi.org/10.1186/s12986-021-00600-0

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