FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY

FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY

Ten substituted pyrazolone derivatives were easily synthesized from perfluorinated allylic alcohols, via a straightforward two steps reaction involving a Heck-coupling/isomerization reaction and subsequent condensation of hydrazines. This fluorous supported methodology, that combines a cyclo-release...

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Main Authors: Nicolas Gouault, Alexandre Cariou, Jean-François Cupif, Patrícia de Aguiar Amaral, Michèle David
Format: Article
Language:English
Published: Sociedade Brasileira de Química
Series:Química Nova
Subjects:
pyrazolones
fluorous tag
Heck coupling
allylic alcohols
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422016000700825&lng=en&tlng=en
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spelling doaj-b6b43b99c1a84c7fa25fd2d26a97938d2020-11-25T00:08:15ZengSociedade Brasileira de QuímicaQuímica Nova1678-706439782583110.5935/0100-4042.20160098S0100-40422016000700825FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGYNicolas GouaultAlexandre CariouJean-François CupifPatrícia de Aguiar AmaralMichèle DavidTen substituted pyrazolone derivatives were easily synthesized from perfluorinated allylic alcohols, via a straightforward two steps reaction involving a Heck-coupling/isomerization reaction and subsequent condensation of hydrazines. This fluorous supported methodology, that combines a cyclo-release approach and F-SPE purification allows for the obtaining of the final products with a good purity.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422016000700825&lng=en&tlng=enpyrazolonesfluorous tagHeck couplingallylic alcohols
collection DOAJ
language English
format Article
sources DOAJ
author Nicolas Gouault
Alexandre Cariou
Jean-François Cupif
Patrícia de Aguiar Amaral
Michèle David
spellingShingle Nicolas Gouault
Alexandre Cariou
Jean-François Cupif
Patrícia de Aguiar Amaral
Michèle David
FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY
Química Nova
pyrazolones
fluorous tag
Heck coupling
allylic alcohols
author_facet Nicolas Gouault
Alexandre Cariou
Jean-François Cupif
Patrícia de Aguiar Amaral
Michèle David
author_sort Nicolas Gouault
title FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY
title_short FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY
title_full FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY
title_fullStr FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY
title_full_unstemmed FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY
title_sort fluorous supported synthesis of pyrazolone derivatives from allylic alcohols using a palladium-catalyzed strategy
publisher Sociedade Brasileira de Química
series Química Nova
issn 1678-7064
description Ten substituted pyrazolone derivatives were easily synthesized from perfluorinated allylic alcohols, via a straightforward two steps reaction involving a Heck-coupling/isomerization reaction and subsequent condensation of hydrazines. This fluorous supported methodology, that combines a cyclo-release approach and F-SPE purification allows for the obtaining of the final products with a good purity.
topic pyrazolones
fluorous tag
Heck coupling
allylic alcohols
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422016000700825&lng=en&tlng=en
work_keys_str_mv AT nicolasgouault fluoroussupportedsynthesisofpyrazolonederivativesfromallylicalcoholsusingapalladiumcatalyzedstrategy
AT alexandrecariou fluoroussupportedsynthesisofpyrazolonederivativesfromallylicalcoholsusingapalladiumcatalyzedstrategy
AT jeanfrancoiscupif fluoroussupportedsynthesisofpyrazolonederivativesfromallylicalcoholsusingapalladiumcatalyzedstrategy
AT patriciadeaguiaramaral fluoroussupportedsynthesisofpyrazolonederivativesfromallylicalcoholsusingapalladiumcatalyzedstrategy
AT micheledavid fluoroussupportedsynthesisofpyrazolonederivativesfromallylicalcoholsusingapalladiumcatalyzedstrategy
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