Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled <it>castle moat </it>surrounding the CNS <it>castle</it>
<p>Abstract</p> <p>Neuronal activity within the central nervous system (CNS) strictly depends on homeostasis and therefore does not tolerate uncontrolled entry of blood components. It has been generally believed that under normal conditions, the endothelial blood-brain barrier (BBB...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-01-01
|
| Series: | Fluids and Barriers of the CNS |
| Online Access: | http://www.fluidsbarrierscns.com/content/8/1/4 |