Trait Impulsivity Associated With Altered Resting-State Functional Connectivity Within the Somatomotor Network

• Main Authors: Aleksandra M. Herman, Hugo D. Critchley, Theodora Duka
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2020-06-01
• Series: Frontiers in Behavioral Neuroscience
• Subjects: trait impulsivity; resting state; functional connectivity; Barratt Impulsiveness Scale; somatomotor network
• Online Access: https://www.frontiersin.org/article/10.3389/fnbeh.2020.00111/full

Knowledge of brain mechanisms underlying self-regulation can provide valuable insights into how people regulate their thoughts, behaviors, and emotional states, and what happens when such regulation fails. Self-regulation is supported by coordinated interactions of brain systems. Hence, behavioral dysregulation, and its expression as impulsivity, can be usefully characterized using functional connectivity methodologies applied to resting brain networks. The current study tested whether individual differences in trait impulsivity are reflected in the functional architecture within and between resting-state brain networks. Thirty healthy individuals completed a self-report measure of trait impulsivity and underwent resting-state functional magnetic resonance imaging. Using Probabilistic Independent Components Analysis in FSL MELODIC, we identified across participants 10 networks of regions (resting-state networks) with temporally correlated time courses. We then explored how individual expression of these spatial networks covaried with trait impulsivity. Across participants, we observed that greater self-reported impulsivity was associated with decreased connectivity of the right lateral occipital cortex (peak mm 46/-70/16, FWE 1-p = 0.981) with the somatomotor network. No supratheshold differences were observed in between-network connectivity. Our findings implicate the somatomotor network, and its interaction with sensory cortices, in the control of (self-reported) impulsivity. The observed “decoupling” may compromise effective integration of early perceptual information (from visual and somatosensory cortices) with behavioral control programs, potentially resulting in negative consequences.