Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.
Considerable controversy exists regarding the exact nature of the molecular mechanism of interfacial activation, a process by which most lipases achieve maximum catalytic activity upon adsorption to an oil water interface. X-ray crystallographic studies show that lipases contain buried active center...
Main Authors: | U Derewenda, L Swenson, Y Wei, R Green, P M Kobos, R Joerger, M J Haas, Z S Derewenda |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1994-03-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520412039 |
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