A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain
BACKGROUND: Neuropathic pain (NP) encompasses many difficult-to-treat disorders. There are few head-to-head, comparative, randomized controlled trials (RCTs) of drugs for NP in different analgesic categories, or of different drugs within a category, despite many placebo-controlled RCTs for individua...
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2010-01-01
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Series: | Pain Research and Management |
Online Access: | http://dx.doi.org/10.1155/2010/382781 |
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doaj-b698a61941f54240b39a5fedfd3d48142020-11-24T23:04:17ZengHindawi LimitedPain Research and Management1203-67652010-01-0115314715710.1155/2010/382781A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic PainC Peter N Watson0Ian Gilron1Jana Sawynok2University of Toronto, Toronto, CanadaQueen’s University, Kingston, Ontario, CanadaDalhousie University, Halifax, Nova Scotia, CanadaBACKGROUND: Neuropathic pain (NP) encompasses many difficult-to-treat disorders. There are few head-to-head, comparative, randomized controlled trials (RCTs) of drugs for NP in different analgesic categories, or of different drugs within a category, despite many placebo-controlled RCTs for individual agents. Well-designed head-to-head comparative trials are an effective way to determine the relative efficacy and safety of a new drug.http://dx.doi.org/10.1155/2010/382781 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
C Peter N Watson Ian Gilron Jana Sawynok |
spellingShingle |
C Peter N Watson Ian Gilron Jana Sawynok A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain Pain Research and Management |
author_facet |
C Peter N Watson Ian Gilron Jana Sawynok |
author_sort |
C Peter N Watson |
title |
A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain |
title_short |
A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain |
title_full |
A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain |
title_fullStr |
A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain |
title_full_unstemmed |
A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain |
title_sort |
qualitative systematic review of head-to-head randomized controlled trials of oral analgesics in neuropathic pain |
publisher |
Hindawi Limited |
series |
Pain Research and Management |
issn |
1203-6765 |
publishDate |
2010-01-01 |
description |
BACKGROUND: Neuropathic pain (NP) encompasses many difficult-to-treat disorders. There are few head-to-head, comparative, randomized controlled trials (RCTs) of drugs for NP in different analgesic categories, or of different drugs within a category, despite many placebo-controlled RCTs for individual agents. Well-designed head-to-head comparative trials are an effective way to determine the relative efficacy and safety of a new drug. |
url |
http://dx.doi.org/10.1155/2010/382781 |
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