A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain

BACKGROUND: Neuropathic pain (NP) encompasses many difficult-to-treat disorders. There are few head-to-head, comparative, randomized controlled trials (RCTs) of drugs for NP in different analgesic categories, or of different drugs within a category, despite many placebo-controlled RCTs for individua...

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Main Authors: C Peter N Watson, Ian Gilron, Jana Sawynok
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2010/382781
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spelling doaj-b698a61941f54240b39a5fedfd3d48142020-11-24T23:04:17ZengHindawi LimitedPain Research and Management1203-67652010-01-0115314715710.1155/2010/382781A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic PainC Peter N Watson0Ian Gilron1Jana Sawynok2University of Toronto, Toronto, CanadaQueen’s University, Kingston, Ontario, CanadaDalhousie University, Halifax, Nova Scotia, CanadaBACKGROUND: Neuropathic pain (NP) encompasses many difficult-to-treat disorders. There are few head-to-head, comparative, randomized controlled trials (RCTs) of drugs for NP in different analgesic categories, or of different drugs within a category, despite many placebo-controlled RCTs for individual agents. Well-designed head-to-head comparative trials are an effective way to determine the relative efficacy and safety of a new drug.http://dx.doi.org/10.1155/2010/382781
collection DOAJ
language English
format Article
sources DOAJ
author C Peter N Watson
Ian Gilron
Jana Sawynok
spellingShingle C Peter N Watson
Ian Gilron
Jana Sawynok
A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain
Pain Research and Management
author_facet C Peter N Watson
Ian Gilron
Jana Sawynok
author_sort C Peter N Watson
title A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain
title_short A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain
title_full A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain
title_fullStr A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain
title_full_unstemmed A Qualitative Systematic Review of Head-to-Head Randomized Controlled Trials of Oral Analgesics in Neuropathic Pain
title_sort qualitative systematic review of head-to-head randomized controlled trials of oral analgesics in neuropathic pain
publisher Hindawi Limited
series Pain Research and Management
issn 1203-6765
publishDate 2010-01-01
description BACKGROUND: Neuropathic pain (NP) encompasses many difficult-to-treat disorders. There are few head-to-head, comparative, randomized controlled trials (RCTs) of drugs for NP in different analgesic categories, or of different drugs within a category, despite many placebo-controlled RCTs for individual agents. Well-designed head-to-head comparative trials are an effective way to determine the relative efficacy and safety of a new drug.
url http://dx.doi.org/10.1155/2010/382781
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