Single-Cell RNA Sequencing Unravels Heterogeneity of the Stromal Niche in Cutaneous Melanoma Heterogeneous Spheroids

Single-Cell RNA Sequencing Unravels Heterogeneity of the Stromal Niche in Cutaneous Melanoma Heterogeneous Spheroids

Heterogeneous spheroids have recently acquired a prominent position in melanoma research because they incorporate microenvironmental cues relevant for melanoma. In this study, we focused on the analysis of microenvironmental factors introduced in melanoma heterogeneous spheroids by different dermal...

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Bibliographic Details
Main Authors: Jiří Novotný, Karolína Strnadová, Barbora Dvořánková, Šárka Kocourková, Radek Jakša, Pavel Dundr, Václav Pačes, Karel Smetana Jr, Michal Kolář, Lukáš Lacina
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
melanoma
spheroids
fibroblasts
subpopulation
heterogeneity
Interleukin-6
Online Access:https://www.mdpi.com/2072-6694/12/11/3324

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