The Effect of Egg Consumption in Hyperlipidemic Subjects during Treatment with Lipid-Lowering Drugs

Background. Limiting egg consumption to avoid high cholesterolemia is recommended to reduce risk of cardiovascular disease. However, recent evidences suggest that cholesterol from diet has limited influence on serum cholesterol. Objective. To assess the effect of egg consumption on lipid profiles in...

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Main Authors: Theerawut Klangjareonchai, Supanee Putadechakum, Piyamitr Sritara, Chulaporn Roongpisuthipong
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Lipids
Online Access:http://dx.doi.org/10.1155/2012/672720
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spelling doaj-b688243c93ba4731b390fef11a1fe1332020-11-24T21:43:47ZengHindawi LimitedJournal of Lipids2090-30302090-30492012-01-01201210.1155/2012/672720672720The Effect of Egg Consumption in Hyperlipidemic Subjects during Treatment with Lipid-Lowering DrugsTheerawut Klangjareonchai0Supanee Putadechakum1Piyamitr Sritara2Chulaporn Roongpisuthipong3Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, ThailandResearch Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, ThailandDepartment of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, ThailandDepartment of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, ThailandBackground. Limiting egg consumption to avoid high cholesterolemia is recommended to reduce risk of cardiovascular disease. However, recent evidences suggest that cholesterol from diet has limited influence on serum cholesterol. Objective. To assess the effect of egg consumption on lipid profiles in hyperlipidemic adults treated with lipid-lowering drugs. Material and Method. Sixty hyperlipidemic subjects, mean age of 61 years, who had been treated with lipid-lowering drugs. Every subject was assigned to consume additional 3 eggs per day with their regular diet for 12 weeks. Measurements for lipid profiles and body compositions were performed. Results. An additional consumption of 3 eggs per day for 12 weeks increased HDL-cholesterol by 2.46±6.81 mg/dL (P<0.01) and decreased LDL-cholesterol to HDL-cholesterol ratio by 0.13±0.46 (P<0.05). No significant changes were found in other lipid profiles. Body weight and body mass index were significantly increased at 12th week by 0.52±1.83 kg and 0.31±0.99 kg/m2, respectively (P<0.05). Conclusion. In hyperlipidemic adults who were treated with lipid-lowering drugs, the consumption of additional 3 eggs per day to their regular diet will increase the level of HDL-cholesterol and decrease the ratio of LDL-cholesterol to HDL-cholesterol.http://dx.doi.org/10.1155/2012/672720
collection DOAJ
language English
format Article
sources DOAJ
author Theerawut Klangjareonchai
Supanee Putadechakum
Piyamitr Sritara
Chulaporn Roongpisuthipong
spellingShingle Theerawut Klangjareonchai
Supanee Putadechakum
Piyamitr Sritara
Chulaporn Roongpisuthipong
The Effect of Egg Consumption in Hyperlipidemic Subjects during Treatment with Lipid-Lowering Drugs
Journal of Lipids
author_facet Theerawut Klangjareonchai
Supanee Putadechakum
Piyamitr Sritara
Chulaporn Roongpisuthipong
author_sort Theerawut Klangjareonchai
title The Effect of Egg Consumption in Hyperlipidemic Subjects during Treatment with Lipid-Lowering Drugs
title_short The Effect of Egg Consumption in Hyperlipidemic Subjects during Treatment with Lipid-Lowering Drugs
title_full The Effect of Egg Consumption in Hyperlipidemic Subjects during Treatment with Lipid-Lowering Drugs
title_fullStr The Effect of Egg Consumption in Hyperlipidemic Subjects during Treatment with Lipid-Lowering Drugs
title_full_unstemmed The Effect of Egg Consumption in Hyperlipidemic Subjects during Treatment with Lipid-Lowering Drugs
title_sort effect of egg consumption in hyperlipidemic subjects during treatment with lipid-lowering drugs
publisher Hindawi Limited
series Journal of Lipids
issn 2090-3030
2090-3049
publishDate 2012-01-01
description Background. Limiting egg consumption to avoid high cholesterolemia is recommended to reduce risk of cardiovascular disease. However, recent evidences suggest that cholesterol from diet has limited influence on serum cholesterol. Objective. To assess the effect of egg consumption on lipid profiles in hyperlipidemic adults treated with lipid-lowering drugs. Material and Method. Sixty hyperlipidemic subjects, mean age of 61 years, who had been treated with lipid-lowering drugs. Every subject was assigned to consume additional 3 eggs per day with their regular diet for 12 weeks. Measurements for lipid profiles and body compositions were performed. Results. An additional consumption of 3 eggs per day for 12 weeks increased HDL-cholesterol by 2.46±6.81 mg/dL (P<0.01) and decreased LDL-cholesterol to HDL-cholesterol ratio by 0.13±0.46 (P<0.05). No significant changes were found in other lipid profiles. Body weight and body mass index were significantly increased at 12th week by 0.52±1.83 kg and 0.31±0.99 kg/m2, respectively (P<0.05). Conclusion. In hyperlipidemic adults who were treated with lipid-lowering drugs, the consumption of additional 3 eggs per day to their regular diet will increase the level of HDL-cholesterol and decrease the ratio of LDL-cholesterol to HDL-cholesterol.
url http://dx.doi.org/10.1155/2012/672720
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