The development of human immune system mice and their use to study tolerance and autoimmunity

Autoimmune diseases evolve from complex interactions between the immune system and self-antigens and involve several genetic attributes, environmental triggers and diverse cell types. Research using experimental mouse models has contributed key knowledge on the mechanisms that underlie these disease...

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Bibliographic Details
Main Authors: Thiago Alves da Costa, Julie Lang, Raul M. Torres, Roberta Pelanda
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Journal of Translational Autoimmunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909019300218