The development of human immune system mice and their use to study tolerance and autoimmunity
Autoimmune diseases evolve from complex interactions between the immune system and self-antigens and involve several genetic attributes, environmental triggers and diverse cell types. Research using experimental mouse models has contributed key knowledge on the mechanisms that underlie these disease...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
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Series: | Journal of Translational Autoimmunity |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589909019300218 |