Adeno-Associated Virus VP1u Exhibits Protease Activity

Adeno-Associated Virus VP1u Exhibits Protease Activity

Adeno-associated viruses (AAVs) are being developed for gene delivery applications, with more than 100 ongoing clinical trials aimed at the treatment of monogenic diseases. In this study, the unique N-terminus of AAV capsid viral protein 1 (VP1u), containing a canonical group XIII PLA<sub>2<...

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Bibliographic Details
Main Authors:	Justin J. Kurian, Renuk Lakshmanan, William M. Chmely, Joshua A. Hull, Jennifer C. Yu, Antonette Bennett, Robert McKenna, Mavis Agbandje-McKenna
Format:	Article
Language:	English
Published:	MDPI AG 2019-04-01
Series:	Viruses
Subjects:	Adeno-associated virus AAV protease phospholipase-A<sub>2</sub> PLA<sub>2</sub>
Online Access:	https://www.mdpi.com/1999-4915/11/5/399

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