Angiotensin-converting enzyme (ACE) inhibitory activity of Solanum torvum and isolation of a novel methyl salicylate glycoside

A methanolic extract from Solanum torvum fruits exhibited inhibitory activity against the angiotensin-converting enzyme (ACE) with an IC50 value of 1.2 mg/mL. On the basis of a bioassay-guided isolation, an ACE inhibitory active compound, namely (E)-2,3-dihydroxycyclopentyl-3-(3′,4′-dihydroxyphenyl)...

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Bibliographic Details
Main Authors: Arunee Simaratanamongkol, Kaoru Umehara, Hiroki Niki, Hiroshi Noguchi, Pharkphoom Panichayupakaranant
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Journal of Functional Foods
Subjects:
ACE
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614002734