Targeted Co-Delivery of Docetaxel and cMET siRNA for Treatment of Mucin1 Overexpressing Breast Cancer Cells

Targeted Co-Delivery of Docetaxel and cMET siRNA for Treatment of Mucin1 Overexpressing Breast Cancer Cells

Purpose: Targeted treatment of breast cancer through combination of chemotherapeutic agents and siRNA had been drawing much attention in recent researches. This study was carried out to evaluate mucin1 aptamer-conjugated chitosan nanoparticles containing docetaxel and cMET siRNA on SKBR3 cells. Meth...

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Bibliographic Details
Main Authors: Naime Majidi Zolbanin, Reza Jafari, Jafar Majidi, Fatemeh Atyabi, Mehdi Yousefi, Farhad Jadidi-Niaragh, Leili Aghebati-Maleki, Dariush Shanehbandi, Mohammad-Sadegh Soltani Zangbar, Alireza Mohajjel Nayebi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-08-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Aptamer
Chitosan
cMET siRNA
Docetaxel
Metastatic breast cancer
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-8-383.pdf

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