An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy.

An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy.

PURPOSE:Recent studies have shown that a new generation of synthetic agonist of Toll-like receptor (TLR) 9 consisting a 3'-3'-attached structure and a dCp7-deaza-dG dinucultodie shows more potent immunostimulatory effects in both mouse and human than conventional CpG oligonucleotides. Radi...

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Bibliographic Details
Main Authors:	Huagang Zhang, Laibin Liu, Dong Yu, Ekambar R Kandimalla, Hui Bin Sun, Sudhir Agrawal, Chandan Guha
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3364192?pdf=render

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