Human subperitoneal fibroblast and cancer cell interaction creates microenvironment that enhances tumor progression and metastasis.

BACKGROUNDS: Peritoneal invasion in colon cancer is an important prognostic factor. Peritoneal invasion can be objectively identified as periotoneal elastic laminal invasion (ELI) by using elastica stain, and the cancer microenvironment formed by the peritoneal invasion (CMPI) can also be observed....

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Bibliographic Details
Main Authors: Motohiro Kojima, Youichi Higuchi, Mitsuru Yokota, Genichiro Ishii, Norio Saito, Kazuhiko Aoyagi, Hiroki Sasaki, Atsushi Ochiai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913740?pdf=render