Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity

The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (2–24) were confirmed by FT-IR, 1H-, 13C-, 11B-, 19F-, and 31P-NMR spectroscopy and mass spectrometry. The ant...

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Main Author: Mouslim Messali
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/8/14936
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spelling doaj-b62edb589e22401e97a79c2a6cfa793b2020-11-24T23:11:58ZengMDPI AGMolecules1420-30492015-08-01208149361494910.3390/molecules200814936molecules200814936Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial ActivityMouslim Messali0Department of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi ArabiaThe present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (2–24) were confirmed by FT-IR, 1H-, 13C-, 11B-, 19F-, and 31P-NMR spectroscopy and mass spectrometry. The antimicrobial activity of all novel ILs was tested against a panel of bacteria and fungi. The results prove that all tested ILs are effective antibacterial and antifungal agents, especially 4-(dimethylamino)-1-(4-phenoxybutyl) pyridinium derivatives 5 and 19.http://www.mdpi.com/1420-3049/20/8/14936eco-friendly synthesisultrasound irradiationionic liquidantimicrobial activity
collection DOAJ
language English
format Article
sources DOAJ
author Mouslim Messali
spellingShingle Mouslim Messali
Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity
Molecules
eco-friendly synthesis
ultrasound irradiation
ionic liquid
antimicrobial activity
author_facet Mouslim Messali
author_sort Mouslim Messali
title Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity
title_short Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity
title_full Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity
title_fullStr Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity
title_full_unstemmed Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity
title_sort eco-friendly synthesis of a new class of pyridinium-based ionic liquids with attractive antimicrobial activity
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2015-08-01
description The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (2–24) were confirmed by FT-IR, 1H-, 13C-, 11B-, 19F-, and 31P-NMR spectroscopy and mass spectrometry. The antimicrobial activity of all novel ILs was tested against a panel of bacteria and fungi. The results prove that all tested ILs are effective antibacterial and antifungal agents, especially 4-(dimethylamino)-1-(4-phenoxybutyl) pyridinium derivatives 5 and 19.
topic eco-friendly synthesis
ultrasound irradiation
ionic liquid
antimicrobial activity
url http://www.mdpi.com/1420-3049/20/8/14936
work_keys_str_mv AT mouslimmessali ecofriendlysynthesisofanewclassofpyridiniumbasedionicliquidswithattractiveantimicrobialactivity
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