Pre- and Postoperative Circulating IGF-I, IGFBP-3, and IGFBP-7 Levels in Relation to Endocrine Treatment and Breast Cancer Recurrence: A Nested Case-Control Study

Pre- and Postoperative Circulating IGF-I, IGFBP-3, and IGFBP-7 Levels in Relation to Endocrine Treatment and Breast Cancer Recurrence: A Nested Case-Control Study

Insulin-like growth factor-I (IGF-I) and its binding proteins (BPs) have been associated with breast cancer risk, especially high IGF-I concentrations and the biologically active fraction estimated as the IGF-I/IGFBP-3 molar ratio. The relation of circulating IGF-I and IGFBP-3 concentrations with ri...

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Bibliographic Details
Main Authors: Ann H. Rosendahl, Sofie Björner, Maria Ygland Rödström, Karin Jirström, Signe Borgquist, Christian Ingvar, Michael N. Pollak, Helena Jernström
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
IGF-I
IGFBP-3
IGFBP-7
IGF-IR
breast cancer
recurrence
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.626058/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.626058/full

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