Tolerating Diabetes: An Alternative Therapeutic Approach for Diabetic Neuropathy
It is becoming apparent that a number of pathogenic mechanisms contribute to diabetic neuropathy, so that therapeutic interventions that target one particular mechanism may have limited success. A recently published preclinical study has adopted an alternative approach by using a novel small molecul...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2010-08-01
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| Series: | ASN Neuro |
| Online Access: | https://doi.org/10.1042/AN20100026 |
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doaj-b6223d924d4b4f07bb0b5d0dadb62e8b2020-11-25T02:54:19ZengSAGE PublishingASN Neuro1759-09141759-90912010-08-01210.1042/AN2010002610.1042_AN20100026Tolerating Diabetes: An Alternative Therapeutic Approach for Diabetic NeuropathyNigel A CalcuttIt is becoming apparent that a number of pathogenic mechanisms contribute to diabetic neuropathy, so that therapeutic interventions that target one particular mechanism may have limited success. A recently published preclinical study has adopted an alternative approach by using a novel small molecule to induce heat-shock protein 70. This confers upon neurons, and perhaps other cells of the nervous system, the ability to better tolerate the diverse stresses associated with diabetes rather than intervening in their production.https://doi.org/10.1042/AN20100026 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Nigel A Calcutt |
| spellingShingle |
Nigel A Calcutt Tolerating Diabetes: An Alternative Therapeutic Approach for Diabetic Neuropathy ASN Neuro |
| author_facet |
Nigel A Calcutt |
| author_sort |
Nigel A Calcutt |
| title |
Tolerating Diabetes: An Alternative Therapeutic Approach for Diabetic Neuropathy |
| title_short |
Tolerating Diabetes: An Alternative Therapeutic Approach for Diabetic Neuropathy |
| title_full |
Tolerating Diabetes: An Alternative Therapeutic Approach for Diabetic Neuropathy |
| title_fullStr |
Tolerating Diabetes: An Alternative Therapeutic Approach for Diabetic Neuropathy |
| title_full_unstemmed |
Tolerating Diabetes: An Alternative Therapeutic Approach for Diabetic Neuropathy |
| title_sort |
tolerating diabetes: an alternative therapeutic approach for diabetic neuropathy |
| publisher |
SAGE Publishing |
| series |
ASN Neuro |
| issn |
1759-0914 1759-9091 |
| publishDate |
2010-08-01 |
| description |
It is becoming apparent that a number of pathogenic mechanisms contribute to diabetic neuropathy, so that therapeutic interventions that target one particular mechanism may have limited success. A recently published preclinical study has adopted an alternative approach by using a novel small molecule to induce heat-shock protein 70. This confers upon neurons, and perhaps other cells of the nervous system, the ability to better tolerate the diverse stresses associated with diabetes rather than intervening in their production. |
| url |
https://doi.org/10.1042/AN20100026 |
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AT nigelacalcutt toleratingdiabetesanalternativetherapeuticapproachfordiabeticneuropathy |
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