Dermatomyositis in patients with autoimmune blistering diseases

• Main Authors: Aikaterini Patsatsi, David R. Pearson, Victoria P. Werth
• Format: Article
• Language: English
• Published: Elsevier 2019-09-01
• Series: International Journal of Women's Dermatology
• Online Access: http://www.sciencedirect.com/science/article/pii/S2352647519300504

It is common for multiple autoimmune diseases to occur in the same patient. However, autoimmune blistering diseases (AIBD) do not commonly associate with dermatomyositis (DM). We performed a literature review and found 12 previous reports that may be attributed to misdiagnosis, underreporting, or true rarity of association. Herein, we present a case of pemphigus vulgaris and a case of mucous membrane pemphigoid associated with DM and review the related literature. AIBD-associated interstitial lung disease, genetic predisposition, potential environmental triggers of both AIBD and DM, drug-related triggers, and paraneoplastic processes are discussed. Dermatologists must be vigilant for a second autoimmune disease in patients with AIBD that may have therapeutic implications. Keywords: Dermatomyositis, interstitial lung disease, pemphigus, pemphigoid, autoimmune, blistering