Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)

The article presents the modern literature data about the prevalence, etiology, pathogenesis of non-alcoholic fatty liver disease in type 2 diabetes mellitus, approaches to the diagnosis and therapy of these patients. The analysis of literature on the risk factors for cardiovascular diseases and cog...

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Main Authors:	O.V. Zemlіanіtsyna, І.P. Dunaeva, V.І. Savenkov, V.M. Sinaіko, Yu.V. Maltseva, N.O. Kravchun
Format:	Article
Language:	English
Published:	Publishing House Zaslavsky 2018-10-01
Series:	Mìžnarodnij Endokrinologìčnij Žurnal
Subjects:	type 2 diabetes mellitus non-alcoholic fatty liver disease cytokines adiponectin leptin resistin fibrosis mar-kers melatonin review
Online Access:	http://iej.zaslavsky.com.ua/article/view/148777

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spelling	doaj-b60e1b87c15243b8aa774923e903a6e22020-11-25T02:28:19ZengPublishing House ZaslavskyMìžnarodnij Endokrinologìčnij Žurnal2224-07212307-14272018-10-0114768469310.22141/2224-0721.14.7.2018.148777148777Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)O.V. Zemlіanіtsyna0І.P. Dunaeva1V.І. Savenkov2V.M. Sinaіko3Yu.V. Maltseva4N.O. Kravchun5State Institution “V. Danіlevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine”, Kharkіv, Ukraine / Educatіonal Scientific Medical Center “Unіversіty Clinic” of Kharkіv National Medical University, Kharkіv, UkraineKharkіv Medical Academy of Postgraduate Educatіon, Kharkіv, UkraineKharkіv National Medical University, Kharkіv, Ukraine / Educatіonal Scientific Medical Center “Unіversіty Clinic” of Kharkіv National Medical University, Kharkіv, UkraineKharkіv National Medical University, Kharkіv, UkraineEducatіonal Scientific Medical Center “Unіversіty Clinic” of Kharkіv National Medical University, Kharkіv, UkraineState Institution “V. Danіlevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine”, Kharkіv, UkraineThe article presents the modern literature data about the prevalence, etiology, pathogenesis of non-alcoholic fatty liver disease in type 2 diabetes mellitus, approaches to the diagnosis and therapy of these patients. The analysis of literature on the risk factors for cardiovascular diseases and cognitive impairment in patients with type 2 diabetes mellitus in non-alcoholic fatty liver disease has been carried out. The role of invasive, minimally invasive and non-invasive methods for assessing the degree of liver fibrosis is shown. The results of own researches, namely determining the features of melatonin excretion in urine and its correlation with the degree of liver fibrosis in patients with type 2 diabetes mellitus in the presence of non-alcoholic fatty liver disease, are given. The results of studying the level of adiponectin in these patients and the role of nutrient therapy to reduce the risk of cardiovascular disorders are presented.http://iej.zaslavsky.com.ua/article/view/148777type 2 diabetes mellitusnon-alcoholic fatty liver diseasecytokinesadiponectinleptinresistinfibrosis mar-kersmelatoninreview
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	O.V. Zemlіanіtsyna І.P. Dunaeva V.І. Savenkov V.M. Sinaіko Yu.V. Maltseva N.O. Kravchun
spellingShingle	O.V. Zemlіanіtsyna І.P. Dunaeva V.І. Savenkov V.M. Sinaіko Yu.V. Maltseva N.O. Kravchun Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data) Mìžnarodnij Endokrinologìčnij Žurnal type 2 diabetes mellitus non-alcoholic fatty liver disease cytokines adiponectin leptin resistin fibrosis mar-kers melatonin review
author_facet	O.V. Zemlіanіtsyna І.P. Dunaeva V.І. Savenkov V.M. Sinaіko Yu.V. Maltseva N.O. Kravchun
author_sort	O.V. Zemlіanіtsyna
title	Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)
title_short	Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)
title_full	Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)
title_fullStr	Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)
title_full_unstemmed	Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)
title_sort	non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)
publisher	Publishing House Zaslavsky
series	Mìžnarodnij Endokrinologìčnij Žurnal
issn	2224-0721 2307-1427
publishDate	2018-10-01
description	The article presents the modern literature data about the prevalence, etiology, pathogenesis of non-alcoholic fatty liver disease in type 2 diabetes mellitus, approaches to the diagnosis and therapy of these patients. The analysis of literature on the risk factors for cardiovascular diseases and cognitive impairment in patients with type 2 diabetes mellitus in non-alcoholic fatty liver disease has been carried out. The role of invasive, minimally invasive and non-invasive methods for assessing the degree of liver fibrosis is shown. The results of own researches, namely determining the features of melatonin excretion in urine and its correlation with the degree of liver fibrosis in patients with type 2 diabetes mellitus in the presence of non-alcoholic fatty liver disease, are given. The results of studying the level of adiponectin in these patients and the role of nutrient therapy to reduce the risk of cardiovascular disorders are presented.
topic	type 2 diabetes mellitus non-alcoholic fatty liver disease cytokines adiponectin leptin resistin fibrosis mar-kers melatonin review
url	http://iej.zaslavsky.com.ua/article/view/148777
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Non-alcoholic fatty liver disease: prevalence, etiology, pathogenesis, approaches to the dіagnosis and therapy (literature review and own data)

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