Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells

Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells

The cytokine gamma interferon (IFN-γ) induces cell-autonomous immunity to combat infections with intracellular pathogens, such as the bacterium Chlamydia trachomatis. The present study demonstrates that IFN-γ-primed human cells ubiquitinate and eliminate intracellular Chlamydia-containing vacuoles,...

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Bibliographic Details
Main Authors: Arun K. Haldar, Anthony S. Piro, Ryan Finethy, Scott T. Espenschied, Hannah E. Brown, Amanda M. Giebel, Eva-Maria Frickel, David E. Nelson, Jorn Coers
Format: Article
Language:English
Published: American Society for Microbiology 2016-12-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/6/e01417-16

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http://mbio.asm.org/cgi/content/full/7/6/e01417-16

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