HBZ and its roles in HTLV-1 oncogenesis

Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL). The minus strand of HTLV-1 provirus encodes a bZIP protein donated as HTLV-1 bZIP factor (HBZ). Among the HTLV-1 regulatory and accessory genes, the tax and HBZ genes were thought to play critical roles in oncogenesis. H...

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Bibliographic Details
Main Authors: Tiejun eZhao, Masao eMatsuoka
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Microbiology
Subjects:
tax
HBZ
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00247/full