Drug-induced-acute liver failure: A critical appraisal of the thioacetamide model for the study of hepatic encephalopathy

Drug-induced-acute liver failure: A critical appraisal of the thioacetamide model for the study of hepatic encephalopathy

Hepatic encephalopathy (HE) following acute and chronic liver failure is defined as a complex of neuropsychiatric abnormalities, such as discrete personal changes, sleep disorder, forgetfulness, confusion, and decreasing the level of consciousness to coma. The use and design of suitable animal model...

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Bibliographic Details
Main Authors: Ali Sepehrinezhad, Ali Shahbazi, Sajad Sahab Negah, Mohammad Taghi Joghataei, Fin Stolze Larsen
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Acute liver failure
Hepatic encephalopathy
Thioacetamide
Toxicity pathway
Animal model
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021000871

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http://www.sciencedirect.com/science/article/pii/S2214750021000871

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