OLIG2 is a novel immunohistochemical marker associated with the presence of PAX3/7-FOXO1 translocation in rhabdomyosarcomas

OLIG2 is a novel immunohistochemical marker associated with the presence of PAX3/7-FOXO1 translocation in rhabdomyosarcomas

Abstract Background The most frequent histological types of rhabdomyosarcoma (RMS) in children are embryonal (ERMS) and alveolar (ARMS) tumours. The majority of ARMS are characterized by the presence of PAX3/7-FOXO1 gene fusion and have a worse prognosis than fusion gene-negative ARMS. However, iden...

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Bibliographic Details
Main Authors: Magdalena Kaleta, Anna Wakulińska, Agnieszka Karkucińska-Więckowska, Bożenna Dembowska-Bagińska, Wiesława Grajkowska, Maciej Pronicki, Maria Łastowska
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Diagnostic Pathology
Subjects:
Rhabdomyosarcoma
OLIG2
ALK
TFAP2B
Immunohistochemistry
Online Access:http://link.springer.com/article/10.1186/s13000-019-0883-4

Internet

http://link.springer.com/article/10.1186/s13000-019-0883-4

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