IMMUNOREGULATORY PROPERTIES OF THROMBOSPONDIN-1, A EXTRACELLULAR MATRIX COMPONENT AND ANGIOGENESIS INHIBITOR

IMMUNOREGULATORY PROPERTIES OF THROMBOSPONDIN-1, A EXTRACELLULAR MATRIX COMPONENT AND ANGIOGENESIS INHIBITOR

Abstract. Thrombospondin-1 (TSP-1) is an extracellular matrix glycoprotein that can positively or negatively regulate adhesion, motility, proliferation, and survival of various cell types, including cells of the immune system. It is secreted by numerous cell types, and its expression is predominant...

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Bibliographic Details
Main Authors: S. A. Kuznetsova, A. V. Krylov, E. P. Kiseleva
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
thrombospondin
extracellular matrix
angiogenesis
inflammation
Online Access:https://www.mimmun.ru/mimmun/article/view/251

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