Deep tissue space-gated microscopy via acousto-optic interaction

In ideal diffraction-limited optical microscopy imaging depth is limited by the multiply scattered wave. Here, the authors present a space gating method, based on an acoustic focus in the object plane and reconstruction using only the acousto-optically modulated ballistic wave, and demonstrate incre...

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Bibliographic Details
Main Authors: Mooseok Jang, Hakseok Ko, Jin Hee Hong, Won Kyu Lee, Jae-Seung Lee, Wonshik Choi
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14514-7
Description
Summary:In ideal diffraction-limited optical microscopy imaging depth is limited by the multiply scattered wave. Here, the authors present a space gating method, based on an acoustic focus in the object plane and reconstruction using only the acousto-optically modulated ballistic wave, and demonstrate increased imaging depth in scattering samples.
ISSN:2041-1723