Plasmon-enhanced stimulated Raman scattering microscopy with single-molecule detection sensitivity

Stimulated Raman scattering (SRS) microscopy enables label-free chemical imaging at high speed, but has been limited by low sensitivity. Here, the authors demonstrate plasmon-enhanced SRS microscopy and achieve single molecule detection sensitivity.

Bibliographic Details
Main Authors: Cheng Zong, Ranjith Premasiri, Haonan Lin, Yimin Huang, Chi Zhang, Chen Yang, Bin Ren, Lawrence D. Ziegler, Ji-Xin Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13230-1