dmLT Adjuvant Enhances Cytokine Responses to T Cell Stimuli, Whole Cell Vaccine Antigens and Lipopolysaccharide in Both Adults and Infants

dmLT Adjuvant Enhances Cytokine Responses to T Cell Stimuli, Whole Cell Vaccine Antigens and Lipopolysaccharide in Both Adults and Infants

Enhancement of mucosal immune responses in children and infants using novel adjuvants such as double mutant heat labile toxin (dmLT) is an important goal in the enteric vaccine field. dmLT has been shown to enhance mucosal IgA responses to the oral inactivated enterotoxigenic Escherichia coli (ETEC)...

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Bibliographic Details
Main Authors: Marjahan Akhtar, Nuder Nower Nizam, Salima Raiyan Basher, Lazina Hossain, Sarmin Akter, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Anna Lundgren
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
dmLT
adjuvant
T cell
monocyte
infants
lipopolysacharide
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.654872/full

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