Invalidation of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Reduces Diet-Induced Low-Grade Inflammation and Adiposity

Invalidation of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Reduces Diet-Induced Low-Grade Inflammation and Adiposity

Chronic low-grade inflammation is known to be linked to obesity, and to occur in the early stages of the disease. This mechanism is complex and involves numerous organs, cells, and cytokines. In this context, inflammation of white adipose tissue seems to play a key role in the development of obesity...

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Bibliographic Details
Main Authors: Clément Pierre, Florent Guillebaud, Coraline Airault, Nathalie Baril, Rym Barbouche, Etienne Save, Stéphanie Gaigé, Bruno Bariohay, Michel Dallaporta, Jean-Denis Troadec
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Physiology
Subjects:
obesity
high-fat diet
mPGES-1
prostaglandins
PGE2
adipose tissue
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01358/full

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https://www.frontiersin.org/article/10.3389/fphys.2018.01358/full

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