Combined deletion of SCD1 from adipose tissue and liver does not protect mice from obesity[S]

Combined deletion of SCD1 from adipose tissue and liver does not protect mice from obesity[S]

Stearoyl-CoA desaturase 1 (SCD1) catalyzes the synthesis of monounsaturated fatty acids (MUFA) from saturated FA. Mice with whole-body or skin-specific deletion of SCD1 are resistant to obesity. Here, we show that mice lacking SCD1 in adipose and/or liver are not protected from either genetic- (agou...

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Bibliographic Details
Main Authors: Matthew T. Flowers, Lacmbouh Ade, Maggie S. Strable, James M. Ntambi
Format: Article
Language:English
Published: Elsevier 2012-08-01
Series:Journal of Lipid Research
Subjects:
stearoyl-CoA
monounsaturated fatty acid
desaturase
desaturation index
oleate
palmitoleate
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520418681

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