Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies

Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies

Cancers have an altered metabolism, and there is interest in understanding precisely how oncogenic transformation alters cellular metabolism and how these metabolic alterations can translate into therapeutic opportunities. Researchers are developing increasingly powerful experimental techniques to s...

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Bibliographic Details
Main Authors: Alexander Muir, Laura V. Danai, Matthew G. Vander Heiden
Format: Article
Language:English
Published: The Company of Biologists 2018-08-01
Series:Disease Models & Mechanisms
Subjects:
Cancer
Cancer models
Metabolism
Microenvironment
Nutrient availability
Nutrient sensing
Online Access:http://dmm.biologists.org/content/11/8/dmm035758

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