Acute Allergic Reaction due to Milk Proteins Contaminating Lactose Added to Corticosteroid for Injection

Acute Allergic Reaction due to Milk Proteins Contaminating Lactose Added to Corticosteroid for Injection

We encountered two patients with severe cow’s milk allergy who reacted strongly to an injection of methylprednisolone sodium succinate (Sol-Medrol 40 mg® Pfizer, Japan). They came to our hospital because of an asthmatic attack or urticaria and were treated with Sol-Medrol 40 mg®. After the injection...

Full description

Bibliographic Details
Main Authors: Asuka Eda, Kazuko Sugai, Hiromi Shioya, Asako Fujitsuka, Setsuko Ito, Tsutomu Iwata, Tetsunori Funabiki
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Allergology International
Subjects:
allergic reaction
cow’s milk allergy
lactose
methylprednisolone sodium succinate
β-lactoglobulin
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015306730
Description
Summary:We encountered two patients with severe cow’s milk allergy who reacted strongly to an injection of methylprednisolone sodium succinate (Sol-Medrol 40 mg® Pfizer, Japan). They came to our hospital because of an asthmatic attack or urticaria and were treated with Sol-Medrol 40 mg®. After the injection, the allergic reaction was immediate. Skin prick tests demonstrated that the β-lactoglobulin contaminating the lactose of the drug preparation caused the immediate allergic reaction.
ISSN:1323-8930

Similar Items