An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes.

An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes.

MIP-T3 is a human protein found previously to associate with microtubules and the kinesin-interacting neuronal protein DISC1 (Disrupted-in-Schizophrenia 1), but whose cellular function(s) remains unknown. Here we demonstrate that the C. elegans MIP-T3 ortholog DYF-11 is an intraflagellar transport (...

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Bibliographic Details
Main Authors: Chunmei Li, Peter N Inglis, Carmen C Leitch, Evgeni Efimenko, Norann A Zaghloul, Calvin A Mok, Erica E Davis, Nathan J Bialas, Michael P Healey, Elise Héon, Mei Zhen, Peter Swoboda, Nicholas Katsanis, Michel R Leroux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2268012?pdf=render

Internet

http://europepmc.org/articles/PMC2268012?pdf=render

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