Irradiation enhanced the effects of PD-1 blockade in brain metastatic osteosarcoma

Brain metastasis of osteosarcoma are rare but carry a dismal prognosis. Despite the advances in both systemic immunotherapy and localized radiation, it is still difficult to treat brain metastasis, with less than 12 months of survival from the time of diagnosis for most patients. Currently, there is...

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Bibliographic Details
Main Authors: Liming Xia, Hao Wu, Wenkang Qian
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Bone Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S221213741830040X